Dartmon SALL4 Antibody (DA106)
IHC (FFPE)
Description
Sal-like protein 4 (SALL4) is a zinc-finger transcription factor1 that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities.2 SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas.1 SALL4 expression is also seen in the spermatogonia of normal testis. — Références — 1. Miettinen M, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014; 38:410-20. 2. Yang J, et al. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. PNAS. 2008; 105:19756-61.
Caractéristiques
- Type
- Recombinant monoclonal mouse antibody
- Clone
- DA106
- Isotype
- Mouse
- Réactivité
- Synthetic peptide of human SALL4
- Localisation
- Nucleus
- Usage prévu
- IHC (FFPE)
Conditionnements disponibles
2 référence(s) catalogue.
| N° catalogue | Type | Dilution | Volume | |
|---|---|---|---|---|
| MMB1A103 | Concentrate | 1:100 – 1:200 | 0.1ml, 0.5ml, 1ml | Demander un devis → |
| MMB1A103 | Ready to use | 1:100 – 1:200 | 3ml, 6ml, 10ml | Demander un devis → |
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