PLAP Antibody (DA199)

Description

Placental Alkaline Phosphatase (PLAP) belongs to a family of four isozymes that are synthesized in primordial germ cells and in term placental syncytiotrophoblasts.1 Anti-PLAP may be useful in the identification of germ cell tumors.2-4 — Références — 1. Fishman L, et al. Developmental phase-specific alkaline phosphatase isoenzymes of human placenta and their occurrence in human cancer. Cancer Res. 1976; 36:2268-73. 2. Stinghen ST, et al. Specific immunoassays for placental alkaline phosphatase as a tumor marker. J Biomed Biotechnol. 2006; 56087:1-8. 3. Ravenni N, et al. A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer. MAbs. 2014; 6:86-94. 4. Jacobsen GK, et al. Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical study. Acta Pathol Microbiol Immunol Scand A. 1984; 92:323-9.

Caractéristiques

Type

Recombinant monoclonal mouse antibody

Clone

DA199

Isotype

Mouse

Réactivité

Synthetic peptide of human PLAP

Localisation

Cell membrane

Usage prévu

IHC (FFPE)