NKX3.1 Antibody (DA236)

Description

NKX3.1 is a prostate specific androgen-regulated homeobox gene located on chromosome 8p.1-2 NKX3.1 expression is seen in benign and malignant prostate epithelium. NKX3.1 is a sensitive and specific tissue marker that can be used to help identify prostate adenocarcinoma.1,2 — Références — 1. Gurel, Bora et al. "NKX3.1 as a marker of prostatic origin in metastatic tumors." The American journal of surgical pathology vol. 34,8 (2010): 1097-105. 2. Chuang, Ai-Ying et al. "Immunohistochemical differentiation of high-grade prostate carcinoma from urothelial carcinoma." The American journal of surgical pathology vol. 31,8 (2007): 1246-55.

Caractéristiques

Type

Recombinant monoclonal rabbit antibody

Clone

DA236

Isotype

Rabbit

Réactivité

Synthetic peptide from human NKX3.1

Localisation

Nucleus

Usage prévu

IHC (FFPE)