Lysozyme Antibody (Polyclonal)

Description

Immunohistochemical study with Lysozyme has been shown to have cytoplasmic expression in hematopoietic cells and non-hematopoietic cells, like renal proximal convoluted tubules.1 Lysozyme may be used as a non-specific marker of tissue macrophages (such as alveolar macrophages and liver Kupffer cells), histiocytes, monocytes, myeloid cells, and their proliferations and neoplasms.1 Anti-lysozyme may aid in the identification of histiocytic lesions and neoplasias, acute myelomonocytic leukemia, acute monocytic leukemia and Langerhans cell histiocytosis.2 — Références — 1. Rehg J, et al. The utility of immunohistochemistry for the identification of hematopoietic and lymphoid cells in normal tissues and interpretation of proliferative and inflammatory lesions of mice and rats. Toxicol Pathol. 2012; 40: 345-74. 2. Seifert RP, et al. A practical approach to diagnose soft tissue myeloid sarcoma preceding or coinciding with acute myeloid leukemia. Annals Diag Pathol. 2014; 18:253-60.

Caractéristiques

Type

Recombinant polyclonal rabbit antibody

Clone

Polyclonal

Isotype

Rabbit

Localisation

Cytoplasm

Usage prévu

IHC (FFPE)