Lambda Light Chain Antibody (DA173)

Description

Anti-lambda detects surface immunoglobulin on normal and neoplastic B-cells. Anti-lambda staining is seen in B-cell follicles of human lymphoid tissue. When dealing with B-cell neoplasms, the determination of light chain ratios remains helpful. Most B-cell lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positive cells. If only a single light chain type is detected, a lymphoproliferative disorder is very likely.1-3 — Références — 1.Abbondanzo SL. Ann Diagn Pathol. 1999; 3:318-27. 2.Kurtin PJ, et al. Am J Clin Pathol. 1999; 112:319-29. 3.Ashton-Key M, et al. Histopathology. 1996; 29:525-31.

Caractéristiques

Type

Recombinant monoclonal mouse antibody

Clone

DA173

Isotype

Mouse

Réactivité

Synthetic peptide of human Lambda Light Chain

Localisation

Cytoplasm

Usage prévu

IHC (FFPE)