Hepatocyte Specific Antigen Antibody (DA070)

Description

Anti-hepatocyte specific antigen, also known as anti-Hep-Par1 (hepatocyte paraffin 1), recognizes both benign and malignant liver-derived tissues including such tumors as hepatocellular carcinoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in identifying hepatocellular carcinomas.1-5 — Références — 1. Minervini, M I et al. "Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc vol. 10,7 (1997): 686-92. 2. Chu, Peiguo G et al. "Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein." The American journal of surgical pathology vol. 26,8 (2002): 978-88. 3. Wieczorek, Tad J et al. "Comparison of thyroid transcription factor-1 and hepatocyte antigen immunohistochemical analysis in the differential diagnosis of hepatocellular carcinoma, metastatic adenocarcinoma, renal cell carcinoma, and adrenal cortical carcinoma." American journal of clinical pathology vol. 118,6 (2002): 911-21. 4. Fasano, M et al. "Immunohistochemical evaluation of hepatoblastomas with use of the hepatocyte-specific marker, hepatocyte paraffin 1, and the polyclonal anti-carcinoembryonic antigen." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc vol. 11,10 (1998): 934-8. 5. Maitra, A et al. "Immunoreactivity for hepatocyte paraffin 1 antibody in hepatoid adenocarcinomas of the gastrointestinal tract." American journal of clinical pathology vol. 115,5 (2001): 689-94.

Caractéristiques

Type

Recombinant monoclonal mouse antibody

Clone

DA070

Isotype

Mouse

Réactivité

Synthetic peptide of human Hepatocyte Specific Antigen

Localisation

Cytoplasm

Usage prévu

IHC (FFPE)