Glycophorin A Antibody (DA247)

Description

Glycophorins A and B are major sialoglycoproteins expressed across the surface of the human erythrocyte membrane and contain the antigenic determinants that define the MNS blood group system.1 The high sialic acid content of glycophorin A contributes to the generation of a net negative surface charge across erythrocyte membranes that minimizes interactions between red blood cells and prevents their aggregation. Anti-glycophorin A has utility in identifying cells of the erythroid lineage.2 — Références — 1. Reid, ME. MNS blood group system: a review. Immunohematology. 2009; 25:95-101 2. Olsen RJ, et al. Acute leukemia immunohistochemistry: a systematic diagnostic approach. Arch Pathol Lab Med. 2008; 132:462-75.

Caractéristiques

Type

Recombinant monoclonal rabbit antibody

Clone

DA247

Isotype

Rabbit

Réactivité

Synthetic peptide of human Glycophorin A

Localisation

Cell membrane

Usage prévu

IHC (FFPE)