Cytokeratin 14 Antibody (DA041)

Description

Cytokeratin 14 is a 50-kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is expressed in most squamous cell carcinomas, in epithelioid mesotheliomas and in the basal-like phenotype of breast carcinoma.1-4 — Références — 1. Reis-Filho, Jorge S et al. "Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast." Applied immunohistochemistry & molecular morphology : AIMM vol. 11,1 (2003): 1-8. 2. Chu, P G et al. "Cytokeratin 14 expression in epithelial neoplasms: a survey of 435 cases with emphasis on its value in differentiating squamous cell carcinomas from other epithelial tumours." Histopathology vol. 39,1 (2001): 9-16. 3. Chu, P G, and L M Weiss. "Cytokeratin 14 immunoreactivity distinguishes oncocytic tumour from its renal mimics: an immunohistochemical study of 63 cases." Histopathology vol. 39,5 (2001): 455-62. 4. Dabbs, DJ. Diagnostic Immunohistochemistry Churchill-Livingstone 2002; 166-176.

Caractéristiques

Type

Recombinant monoclonal rabbit antibody

Clone

DA041

Isotype

Rabbit

Localisation

Cytoplasm

Usage prévu

IHC (FFPE)