BIO SB Vimentin (EP21), RMab
For In Vitro Diagnostic Use
Description
Vimentin is a member of the intermediate filament family of proteins. Intermediate filaments are an important structural feature of eukaryotic cells. Together with microtubules and actin microfilaments, they make up the cytoskeleton. Expression of vimentin antibody, when used in conjunction with keratin, is helpful in distinguishing melanomas from Undifferentiated Carcinomas and Large-Cell Lymphomas. All Melanomas and Schwannomas react strongly with vimentin. This antibody recognizes a 57 kDa intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymph cells, endothelial cells and fibroblasts. Non-reactivity of vimentin antibody is often considered more useful than its presence, since there are a few tumors that do not contain vimentin (e.g., Hepatoma and Seminoma).
Synonymes
VIM, anti-Vimentin, anti Vimentin, anti VIM, anti-VIM, FLJ36605, Vimentin, stem cell progenitor progenitor cell
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP21
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Tonsil, Lymph Node, Colon
- Usage prévu
- For In Vitro Diagnostic Use
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