BIO SB Tyrosinase (BSB-6), MMab
For In Vitro Diagnostic Use
Description
Tyrosinase is an enzyme that catalyzes the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. The gene for Tyrosinase is regulated by the Microphthalmia-associated transcription factor. A mutation in the tyrosinase gene leads to impaired tyrosinase production resulting in Type I Oculocutaneous Albinism, a hereditary disease that affects 1 in 17,000 people in the U.S. Tyrosinase antibody has been found to be quite specific for melanotic lesions such as Malignant Melanoma and Melanotic Neurofibroma. Essentially no carcinomas express this marker.
Synonymes
TYR, santi-Tyrosinase, anti Tyrosinase, anti-TYR, anti TYR, LB24 AB, Monophenol monooxygenase, OCA1A, OCAIA, SHEP3, SK29 AB, tumor rejection antigen AB, Tyrosinase, tyrosinase oculocutaneous albinism IA, Tyrosinase precursor, Albino locus protein, CMM8
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-6
- Isotype
- IgG2a
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Skin, Malignant Melanoma
- Usage prévu
- For In Vitro Diagnostic Use
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