Tryptase (G3), MMab
For In Vitro Diagnostic Use
Description
Tryptase is the most abundant secretory granule-derived serine proteinase contained in mast cells and has recently been used as a marker for mast cell activation. It is involved in allergenic response and is suspected to act as a mitogen for fibroblast lines. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis. Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. Human mast cell tryptase is considered to be an important marker of mast cell activation as well as an important mediator of inflammation. Tryptase antibody is a good marker for mast cells, basophils, and their derivatives.
Synonymes
PSAB1, Tpsb2, tryptase alpha beta 1, TPS1, TPS2, TPSB1, anti-tryptase, anti tryptase, mass cell tryptase, mct, anti mct, anti mct, TPS1, TPS2, TPSB1, tryptase alpha II, tryptase alpha beta 1, tryptase beta 1, tryptase beta I, Tryptase beta 2, Tryptase II, Tryptase 2, tryptase I, tryptase III, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase beta II, mast cell tryptase beta III, TPSB2, tryptase beta II, tryptase beta III, tryptaseB, tryptaseC, Tryptase alpha 1, tryptase beta 2 gene pseudogene, Tryptase 1
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- G3
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Mast Cell Containing Tissues, Uterus
- Usage prévu
- For In Vitro Diagnostic Use
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