BIO SB TNFa-IP2 (BSB-141), MMab
For In Vitro Diagnostic Use
Description
Tumor Necrosis Factor alpha Induced-Protein 2 (also known as B94) is a 73‐kDa polypeptide involved in pathways of inflammation, metastasis, tumor vasculature, and angiogenesis. The protein has an exocyst complex, Dsl1 complex, conserved oligomeric Golgi (COG) complex and the Golgi‐associated retrograde protein (GARP) complex. TNFa-IP2 antibody expression is found in epithelial cells, and immune cells exposed to Tumor Necrosis Factor alpha (TNFa), IL-1beta, LPS, interferon-y, Retinoic Acid, Latent Membrane Protein 1 (LMP1), and other pro-inflammatory cytokines. TNFa-IP can inhibit NFKB to further reduce inflammation in renal dysfunction and septic shock. and can interact with GTPases to regulate breast cancer and HeLa cell actin cytoskeleton and cell structure. TNFa-IP2 also participates in T-cell migration as an inflammatory regulator of chemokine secretion, and promotes metastasis and microvessel formation in nasopharyngeal carcinoma.
Synonymes
tnfaip2, tnfa, tnfaip, tnfa-ip2, anti-tnfa-ip2, anti-tnfaip2 anti-tnfa, anti-tnfaip, Tumor Necrosis Factor alpha Induced-Protein 2, anti-B94, b94 antibody, cytokine storm, cytokine storm syndrome, cytokine storm antibody, cytokine storm antibodies, sars-cov-2 receptors, sars cov-2 receptors, covid-19 receptors, sars-cov-2 antibodies sars-cov-2 ihc, sars-cov-2 immunohistochemistry, TNFalpha IP 2, TNF alpha induced protein 2, EXOC3L3, exocyst complex component 3 like 3
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-141
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Testis, Tonsil, Lung, Kidney
- Usage prévu
- For In Vitro Diagnostic Use
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