BIO SB TCR Beta (BSB-117), MMab
For In Vitro Diagnostic Use
Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. TCR Beta is a member of the immunoglobin super family and a component of the CD3/TCR complex (along with TCR Alpha). TCR Beta antibody is expressed by thymocytes and a majority of peripheral (α-β TCR-bearing) T-cells. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors.
Synonymes
TCR β, TCR beta, BV05S1J2 2, MGC88817, T cell receptor beta constant 1, TCRBC1, TRBC1, T cell receptor beta 1 chain C region2, anti-tcr beta, anti tcr beta, anti-TCR β, anti TCR β
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-117
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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