BIO SB TCR Alpha (BSB-126), MMab
For In Vitro Diagnostic Use
Description
TCR Alpha antibody detects T-cell receptor alpha locus, a protein that in humans is encoded by the TRA gene, also known as TCRA or TRAα; It contributes the alpha chain to the larger TCR protein (T-cell receptor). The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. This ratio changes during ontogeny and in cancers, such as Leukemia.
Synonymes
TCR α, TCR alpha, TRA, anti-TCR α, anti TCR α, TCR-α, anti-TCR-α, anti TCR-α, anti-tcr alpha, anti tcr alpha
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-126
- Isotype
- IgG2a/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Thymus, Tonsil, Lymph Node, Spleen, Hodgkin’s Lymphoma & BDCM & CCRF-CEM Cell Lines
- Usage prévu
- For In Vitro Diagnostic Use
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