Progen Matériel de laboratoire
Synaptophysin (RBT-Synaptophysin), RMab

Synaptophysin (RBT-Synaptophysin), RMab

For In Vitro Diagnostic Use

Clone RBT-Synaptophysin IgG Rabbit Monoclonal

Description

Synaptophysin is a synaptic vesicle glycoprotein weighing 38 kDa. It consists of four transmembrane domains and the protein is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. This antibody identifies both normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely-granular cytoplasmic staining is observed and probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers making synaptophysin an independent broad-range marker of neural and neuroendocrine differentiation.

Synonymes

synaptophysin, SYP, anti-SYP, anti SYP, anti-Synaptophysin, anti Synaptophysin, Major synaptic vesicle protein p38, MRXSYP

Caractéristiques

Type
Rabbit Monoclonal
Clone
RBT-Synaptophysin
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Cytoplasmic
Contrôle
Pancreas, Brain, Pituitary, Adrenal, Colon
Usage prévu
For In Vitro Diagnostic Use

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