BIO SB Synaptophysin (Polyclonal), RPab
For In Vitro Diagnostic Use
Description
Synaptophysin is a synaptic vesicle glycoprotein weighing 38 kDa. It is present in endocrine cells, the brain, spinal cord, and adrenal glands. It acts as a marker for neuroendocrine cells. Synaptophysin antibody reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, and Paneth’s cells in the gastrointestinal tract and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely-granular cytoplasmic staining is observed and probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of Synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Synaptophysin is an independent broad-range marker of neural and neuroendocrine differentiation.
Synonymes
synaptophysin, SYP, anti-SYP, anti SYP, anti-Synaptophysin, anti Synaptophysin, Major synaptic vesicle protein p38, MRXSYP
Caractéristiques
- Type
- Rabbit Polyclonal
- Clone
- N/A
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Pancreas, Brain, Pituitary, Adrenal, Colon
- Usage prévu
- For In Vitro Diagnostic Use
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