BIO SB Spectrin (RBC2/3D5), MMab
For In Vitro Diagnostic Use
Description
Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh. Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Spectrin antibody is useful in the diagnosis of Erythroid Leukemias.
Synonymes
SPTAN1, spectrin α II, spectrin alpha II, alpha II spectrin, FLJ44613, fodrin alpha chain, NEAS, Spectrin alpha chain brain, spectrin alpha non erythrocytic 1 alpha fodrin, spectrin non erythroid alpha chain, EIEE5, FLJ17738, SPTA2
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- RBC2/3D5
- Isotype
- IgG2b/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Bone Marrow, Spleen
- Usage prévu
- For In Vitro Diagnostic Use
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