BIO SB Somatostatin (BSB-113), MMab
For In Vitro Diagnostic Use
Description
Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and by inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids; the other of 28 amino acids. Somatostatin is secreted not only by cells of the hypothalamus but also by the stomach, intestine, and delta cells of the pancreas. It binds to somatostatin receptors. Somatostatin antibody is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify hyperplasia of the pancreatic islets. Most of these tumors are malignant, giving rise to Somatostatinomas. Somatostatin suppresses gastric acid secretion, gallbladder contractions and pancreatic enzyme secretion.
Synonymes
Smst, Sst, anti-Somatostatin, anti Somatostatin, anti-SST, anti SST, anti-SMST, anti SMST, Antrin, Growth hormone release inhibiting factor, preprosomatostatin, SOM, Somatostatin, Somatostatin 14, Somatostatin 28, SRIF, SS
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-113
- Isotype
- IgG2a/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Pancreas, Colon, Adrenal, Brain
- Usage prévu
- For In Vitro Diagnostic Use
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