BIO SB pTau Phospho (BSB-176), MMab
For In Vitro Diagnostic Use
Description
Tau is a phosphorylated protein, containing 85 potential serine (S), threonine (T), and tyrosine (Y) phosphorylation sites. Both the phosphorylation status and isoform expression of tau are developmentally regulated and both are important factors for cytoskeletal plasticity during embryogenesis and early development. Despite the significant heterogeneity that exists between and within the various tauopathies, the deposited tau in pathological lesions is invariably highly phosphorylated. Characteristic accumulations of highly phosphorylated tau protein (Thr 181) aggregates are found in several neurodegenerative tauopathies including Alzheimer’s Disease (AD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), and some forms of Frontotemporal Lobar Dementia (FTLD-tau).
Synonymes
MAPT, microtubule associated protein tau, p Tau, sc32275, phospho Tau, phosphorylated Tau, p- Tau, pTau, anti MAPT, anti microtubule associated protein tau, anti p Tau, anti p-Tau, anti pTau, anti-MAPT, anti-microtubule associated protein tau, anti-p Tau, anti-p-Tau, anti-pTau, DDPAC, FLJ31424, FTDP 17, G protein beta1 gamma2 subunit interacting factor 1, MAPTL, microtubule associated protein tau isoform 4, MSTD, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PPND, TAU, TPA
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-176
- Isotype
- IgG1K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Perinuclear,
- Contrôle
- Brain
- Usage prévu
- For In Vitro Diagnostic Use
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