BIO SB Podoplanin / D2-40 (D2-40), MMab
For In Vitro Diagnostic Use
Description
Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin antibody is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi’s Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.
Synonymes
AGGRUS, Gp36, PDPN, anti-podoplanin, anti podoplanin, anti-PDPN, anti PDPN, anti-GP36, anti GP36, anti-Aggrus, anti Aggrus, glycoprotein 36, glycoprotein 36 KD, Gp38, GP40, HT1A 1, hT1alpha 1, hT1alpha 2, lung type I cell membrane associated glycoprotein, lung type I cell membrane associated glycoprotein T1A 2, OTS8, PA2 26, PA2 26 antigen, Podoplanin, T1 alpha, T1A, T1A 2
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- D2-40
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Tonsil, Lymph Node, Lymphangioma
- Usage prévu
- For In Vitro Diagnostic Use
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