PAX-2 (EP235), RMab
For In Vitro Diagnostic Use.
Description
PAX-2 is a homeogene strongly expressed during kidney development. PAX-2 gene is expressed in the metanephric mesenchyma after ureter bud induction and is a key factor for the mesenchyma-epithelium conversion. Animals transgenic for PAX-2 have severe renal abnormalities and cysts but no solid tumoral features. PAX-2 antibody can be used to distinguish Ovarian Serous Papillary Carcinoma (PAX-2 positive) from Primary Breast Carcinoma (PAX-2 negative). It can also be used to distinguish Clear Cell Renal Carcinoma (positive) from Hepatocellular Carcinoma (negative).
Synonymes
Pax2, Pax 2, anti-Pax-2, anti Pax-2, anti-Pax 2, anti-Pax2, anti Pax 2, anti Pax2, paired box 2, paired box homeotic gene 2, Paired box protein Pax 2
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP235
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Kidney, Fallopian Tube, Clear Cell Renal Carcinoma, Ovarian Serous Papillary Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use.
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