Progen Matériel de laboratoire

Description

PAX-2 is a homeogene strongly expressed during kidney development. PAX-2 gene is expressed in the metanephric mesenchyma after ureter bud induction and is a key factor for the mesenchyma-epithelium conversion. Animals transgenic for PAX-2 have severe renal abnormalities and cysts but no solid tumoral features. PAX-2 antibody can be used to distinguish Ovarian Serous Papillary Carcinoma (PAX-2 positive) from Primary Breast Carcinoma (PAX-2 negative). It can also be used to distinguish Clear Cell Renal Carcinoma (positive) from Hepatocellular Carcinoma (negative).

Synonymes

Pax2, Pax 2, anti-Pax-2, anti Pax-2, anti-Pax 2, anti-Pax2, anti Pax 2, anti Pax2, paired box 2, paired box homeotic gene 2, Paired box protein Pax 2

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP235
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Nuclear
Contrôle
Kidney, Fallopian Tube, Clear Cell Renal Carcinoma, Ovarian Serous Papillary Carcinoma
Usage prévu
For In Vitro Diagnostic Use.

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