p63 (EP174), RMab
For In Vitro Diagnostic Use
Description
p63 is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. In addition to p53, mammalian cells contain two homologous genes, p63 and p73. These genes give rise to the expression of proteins that are highly similar to p53 in structure and function. In particular, p63 and p73 proteins can induce p53-responsive genes and elicit programmed cell death. p73 and p63 are more important during development and differentiation. In particular, p63 appears to be primarily implicated in epithelial development. p63 antibody to human p63 protein labels an epitope common to all six p63 isotypes (TAp63α, TAp63β, TAp63γ, ΔNp63α, ΔNp63β, ΔNp63γ). p63 labels the nuclei of myoepithelial cells in the prostate gland as well as breast tissue, making it useful in differentiating benign vs. malignant prostate lesions and breast lesions.
Synonymes
p63, p-63, p 63, anti-p63, anti-p-63, anti-p 63, anti p63, anti p-63, anti p 63, TP63, Trp63, anti-TP63, anti-Trp63, anti TP63, anti Trp63, anti p53cp, anti TP53CP, anti tumor protein p63, anti-p53cp, anti-TP53CP, anti-tumor protein p63, p53cp, TP53CP, tumor protein p63
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP174
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Prostate, Breast, Skin, Salivary Gland
- Usage prévu
- For In Vitro Diagnostic Use
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BIO SB