BIO SB p120 Catenin (EP66), RMab
For In Vitro Diagnostic Use
Description
p120 Catenin antibody is a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Cytoplasmic accumulation of p120 Catenin has been observed in lung cancer, pancreatic cancer, gastric cancer and colon cancers and is associated with poor prognosis in colon cancer patients. In breast lobular neoplasia, p120 Catenin antibody shows a diffuse cytoplasmic immunostaining pattern, while breast ductal neoplasia retains the membrane immunostaining pattern. p120 Catenin can be useful in differentiating between lobular carcinoma and ductal carcinoma of the breast, and in identifying early lesions of lobular neoplasia.
Synonymes
Ctnnd1, Cadherin associated Src substrate, CAS, catenin cadherin associated protein delta 1, Catenin delta 1, catenin src, Catns, Ctnnd, mKIAA0384, P120, p120 catenin, p120 cas, p120 ctn, anti-p120, anti p120, anti-catenin, anti catenin,
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP66
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous, Cytoplasmic
- Contrôle
- Breast, Testis, Kidney, Prostate, Pancreas, Tonsil, Salivary Gland, Skin, Cervix, Colon, Malignant Melanoma, Transitional Cell Carcinoma, Breast Lobular Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use
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