Progen Matériel de laboratoire

Description

Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 antibody is expressed in mature B cells, predominantly germinal center B cells. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas.

Synonymes

homeobox protein, Lymphoid restricted immunoglobulin octamer binding protein NF A2, Oct 2, Oct2, octamer binding transcription factor 2, OTF 2, OTF2, POU class 2 homeobox 2, POU domain class 2 transcription factor 2, POU2F2, Octamer binding protein 2, anti-oct-2, anti oct-2, anti-oct2, anti oct2, anti-oct-2, anti oct-2

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP115
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Nuclear
Contrôle
Tonsil, Lymph Node
Usage prévu
For In Vitro Diagnostic Use

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