BIO SB Napsin A (BSB-112), MMab
For In Vitro Diagnostic Use
Description
The activation peptides of aspartic proteinases play a role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional glycosylated aspartic proteinase precursor containg an RGD motif and an addition 18 residues at its C-terminus. In normal tissue, anti-Napsin A antibody labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is a useful marker for lung adenocarcinoma.
Synonymes
NAPSA, napsin A aspartic peptidase, KAP, Kdap, NAP1, NAPA, SNAPA, anti-napsin a, anti napsin a, napsin-a, anti-napsin-a, anti napsin-a
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-112
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Kidney, Lung, Renal Cell Carcinoma, Lung Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use
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