Progen Matériel de laboratoire

Description

Myoglobin is a single-chain globular protein of 153 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. With a molecular weight of 16.7 kDa, Myoglobin is the primary oxygen-carrying pigment of muscle tissues. Immunostaining with Myoglobin antibody provides a specific, sensitive and practical procedure for the identification of Rhabdomyosarcoma. Since myoglobin is found exclusively in skeletal and cardiac muscle, it may be used to distinguish Rhabdomyosarcoma from other soft-tissue tumors. Myoglobin antibody staining is also useful when demonstrating rhabdomyoblastic differentiation in other tumors, e.g., Neurogenic Sarcomas and Malignant Mixed Mesodermal Tumors of the uterus and ovary.

Synonymes

MB, anti-Myoglobin, anti myoglobin, PVALB

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP87
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Cytoplasmic
Contrôle
Skeletal Muscle Tissue
Usage prévu
For In Vitro Diagnostic Use

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