BIO SB Myogenin (F5D), MMab
For In Vitro Diagnostic Use
Description
Myogenin is a transcription factor active in muscles. In particular, it is a myogenic regulatory factor. Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin antibody is restricted to cells of skeletal-muscle origin. It is, therefore, a useful marker for tumors of the muscle lineage, being strongly expressed in Alveolar Rhabdomyosarcomas. Myogenin antibody labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of Rhabdomyosarcoma and some Leiomyosarcomas. Positive nuclear staining may occur in Wilm’s Tumor.
Synonymes
Myog, anti-myogenin, anti myogenin, MyoD1, anti-MyoD1, anti MyoD1, Myogenin, bHLHc3, Myf 4, MYF4, myogenic factor 4, Myogenic factor 4 myogenin, myogenin myogenic factor 4, OTTHUMP00000039094, MYOD1 related protein
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- F5D
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Rhabdomyosarcoma
- Usage prévu
- For In Vitro Diagnostic Use
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