Progen Matériel de laboratoire

Description

MyoD1 belongs to a family of proteins known as myogenic regulatory factors (MRFs) and has a key role in regulating muscle differentation. These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MyoD1 antibody is expressed in activated satellite cells, but not in quiescent satellite cells. In development, MyoD1 commits mesoderm cells to a skeletal lineage, and then regulates that process. It may also play a role in muscle repair. In abnormal tissues, MyoD1 antibody labels tumor cells in Rhabdomyosarcoma and is one of the earliest markers of myogenic commitment.

Synonymes

MYOD1, anti-MyoD, anti MyoD, anti-MYOD1, anti MYOD1, myogenic differentiation 1, MYF3, MYOD, PUM, bHLHc1

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP212
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Nuclear
Contrôle
Fetal Muscle, Rhabdomyosarcoma
Usage prévu
For In Vitro Diagnostic Use

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