MyoD1 (EP212), RMab
For In Vitro Diagnostic Use
Description
MyoD1 belongs to a family of proteins known as myogenic regulatory factors (MRFs) and has a key role in regulating muscle differentation. These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MyoD1 antibody is expressed in activated satellite cells, but not in quiescent satellite cells. In development, MyoD1 commits mesoderm cells to a skeletal lineage, and then regulates that process. It may also play a role in muscle repair. In abnormal tissues, MyoD1 antibody labels tumor cells in Rhabdomyosarcoma and is one of the earliest markers of myogenic commitment.
Synonymes
MYOD1, anti-MyoD, anti MyoD, anti-MYOD1, anti MYOD1, myogenic differentiation 1, MYF3, MYOD, PUM, bHLHc1
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP212
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Fetal Muscle, Rhabdomyosarcoma
- Usage prévu
- For In Vitro Diagnostic Use
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