BIO SB MUM1 (EP190), RMab
For In Vitro Diagnostic Use
Description
MUM1 (multiple myeloma oncogene-1) also known as interferon regulatory factor 4 (IRF4) is a 50 kDa protein and is a member of the interferon regulatory factor family of transcription factors. It is induced by antigen receptor mediated stimuli and plays an important role in cell proliferation, differentation and survival. MUM1 antibody is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B-cells commited to plasmacytic or memory cell differentation in the “light zone”. MUM1 is useful for subclassification of lymphoid malignancies and is an excellent marker for Hodgkin’s and Reed-Sternberg cells of classic Hodgin’s disease.
Synonymes
MUM1, melanoma associated antigen mutated 1, EXPAND1, HSPC211, MUM 1, mum-1, anti-mum1, anti-mum-1, anti mum1, anti mum-1
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP190
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Nuclear
- Contrôle
- Tonsil, Lymph Node, Plasmacytoma, Hodgkin’s Lymphoma
- Usage prévu
- For In Vitro Diagnostic Use
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