BIO SB Lambda (BSB-16), MMab
For In Vitro Diagnostic Use
Description
Lambda antibody detects surface immunoglobulin on normal and neoplastic B-cells. Lambda staining is seen in B-cell follicles of human lymphoid tissue. When studying B-cell neoplasms, the determination of light chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lymphoproliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or moreof the total population.
Synonymes
IGLL1, immunoglobulin lambda like polypeptide 1, 14 1, AGM2, CD179b, IGL1, IGL5, IGLJ14 1, IGLL, IGO, IGVPB, VPREB2, anti-lambda, anti lambda, igll, anti-igll, anti igll
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-16
- Isotype
- IgG2a
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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