Progen Matériel de laboratoire

Description

Ki-67 is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. The Ki-67 protein is a cellular marker for proliferation. It is strictly associated with cell proliferation. During the interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). The Ki-67 antibody is an excellent marker to determine the growth fraction of a given cell population. The fraction of Ki-67 positive tumor cells (the Ki-67 labeling index) is often correlated with the clinical course of cancer. The best-studied examples in this context are carcinomas of the prostate and the breast.

Synonymes

ki67, ki -67, ki- 67, ki 67, ki-56, anti ki67, anti ki-67, anti ki 67, anti-ki67, anti-ki-67, anti-ki 67, antigen identified by monoclonal antibody Ki 67, Antigen KI 67, KIA, MKI67, proliferation related Ki 67 antigen

Caractéristiques

Type
Rabbit Monoclonal
Clone
RM360
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Nuclear
Contrôle
Testis, Tonsil, Bone Marrow, Placenta, colon, Tonsil, Fallopian tube, Astrocytoma, Breast Carcinoma, Colon Carcinoma

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