Ki-67 (EP5), RMab
For In Vitro Diagnostic Use
Description
Ki-67 is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. The Ki-67 protein is a cellular marker for proliferation. It is strictly associated with cell proliferation. During the interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). The Ki-67 antibody is an excellent marker to determine the growth fraction of a given cell population. The fraction of Ki-67 positive tumor cells (the Ki-67 labeling index) is often correlated with the clinical course of cancer. The best-studied examples in this context are carcinomas of the prostate and the breast.
Synonymes
ki67, ki -67, ki- 67, ki 67, ki-56, anti ki67, anti ki-67, anti ki 67, anti-ki67, anti-ki-67, anti-ki 67, antigen identified by monoclonal antibody Ki 67, Antigen KI 67, KIA, MKI67, proliferation related Ki 67 antigen
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP5
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Testis, Tonsil, Bone Marrow, Placenta, colon, Tonsil, Fallopian tube, Astrocytoma, Breast Carcinoma, Colon Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use
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BIO SB