BIO SB IgD (EP173), RMab
For In Vitro Diagnostic Use
Description
IgD makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes (coexpressed with IgM) and is also found in serum in very small amounts. It is monomeric and incorporates the alpha-heavy chain in its structure. IgD’s function is currently unknown, as mice lacking IgD seem to retain normal immune responses (implying redundancy if not lack of function), and IgD ceases to be expressed in activated B-lymphocytes. It may function as a regulatory antigen receptor. IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived from Lymphomas, specifically Marginal Zone Lymphoma.
Synonymes
Ig delta chain C region, IGHD, immunoglobulin heavy constant delta, MGC29633, anti-igd, anti igd, anti-ig delta, anti ig delta
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP173
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Tonsil, Lymph Node, Spleen
- Usage prévu
- For In Vitro Diagnostic Use
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