Progen Matériel de laboratoire

Description

HER-2 neu is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. HER-2 neu (also known as c-erbB-2) is a member of the epidermal growth factor receptor (EGFR) family and is notable for its role in the pathogenesis of breast cancer and as a target of treatment. It is a cell membrane surface-bound tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER-2 neu is a proto-oncogene located at the long arm of human chromosome 17(17q11.2-q12).

Synonymes

ERBB2, HER2, anti ERBB2, anti HER2, anti Neu, anti-ERBB2, anti-HER2, anti-Neu, c erb B2 neu protein, CD340, HER 2, HER 2 neu, herstatin, NEU, neuroblastoma glioblastoma derived oncogene homolog, NGL, p185erbB2, Receptor tyrosine protein kinase erbB 2, TKR1, tyrosine kinase type cell surface receptor HER2, v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 neuro glioblastoma derived oncogene homolog, v erb b2 erythroblastic leukemia viral oncogene homolog 2 neuro glioblastoma derived oncogene homolog avian, Metastatic lymph node gene 19 protein, Proto oncogene c ErbB 2, proto oncogene Neu

Caractéristiques

Type
Rabbit Monoclonal
Clone
RBT-HER2
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Membranous
Contrôle
Breast Carcinoma

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