BIO SB anticorps automates-ihc reactifs-auxiliaires

Granzyme B (EP230), RMab

For In Vitro Diagnostic Use

Clone EP230 IgG Rabbit Monoclonal

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Description

Granzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them. Granzyme B antibody has been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s Disease.

Synonymes

anti-granzyme b, anti granzyme b, anti-gb, anti gb, GZMB, granzyme B granzyme 2 cytotoxic T lymphocyte associated serine esterase 1, CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, HLP, SECT

Caractéristiques

Type: Rabbit Monoclonal
Clone: EP230
Isotype: IgG
Réactivité: Paraffin, Frozen
Localisation: Cytoplasmic (Granular)
Contrôle: Liver, Testis, Cervix, Tonsil, Lymph Node, Spleen
Usage prévu: For In Vitro Diagnostic Use

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