Galectin-3 (9C4), MMab
For In Vitro Diagnostic Use
Description
Galectin-3 is a 31 kDa beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Galectin-3 antibody has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and Fine Needle Aspiration Biopsy material. Galectin-3 antibody has also been useful in identifying Anaplastic Large Cell Lymphoma.
Synonymes
GAL3, galectin 3, LGALS3, anti-galectin-3, anti galectin-3, anti-galectin 3, anti-galectin3, anti galectin 3, anti galectin3, anti-LGALS3, anti LGALS3, anti-GAL3, anti GAL3, 35 kDa lectin, carbohydrate binding protein 35, CBP 35, CBP35, Galactose specific lectin 3, Galactoside binding protein, GALBP, GALIG, IgE binding protein, L 31, Laminin binding protein, lectin L 29, lectin galactoside binding soluble 3, LGALS2, Mac 2 antigen, MAC2, GBP, L 34, L 34 galactoside binding lectin, lectin galactose binding soluble 3, Mac 2, galctin, Gal 3, L31
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- 9C4
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Kidney, Testis, Salivary Gland, Breast, Tonsil, Colon, Papillary, Follcular Carcinoma of Thyroid
- Usage prévu
- For In Vitro Diagnostic Use
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