Progen Matériel de laboratoire

Description

Galectin-3 is a 31 kDa beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Galectin-3 antibody has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and Fine Needle Aspiration Biopsy material. Galectin-3 antibody has also been useful in identifying Anaplastic Large Cell Lymphoma.

Synonymes

GAL3, galectin 3, LGALS3, anti-galectin-3, anti galectin-3, anti-galectin 3, anti-galectin3, anti galectin 3, anti galectin3, anti-LGALS3, anti LGALS3, anti-GAL3, anti GAL3, 35 kDa lectin, carbohydrate binding protein 35, CBP 35, CBP35, Galactose specific lectin 3, Galactoside binding protein, GALBP, GALIG, IgE binding protein, L 31, Laminin binding protein, lectin L 29, lectin galactoside binding soluble 3, LGALS2, Mac 2 antigen, MAC2, GBP, L 34, L 34 galactoside binding lectin, lectin galactose binding soluble 3, Mac 2, galctin, Gal 3, L31

Caractéristiques

Type
Mouse Monoclonal
Clone
9C4
Isotype
IgG1
Réactivité
Paraffin, Frozen
Localisation
Cytoplasmic
Contrôle
Kidney, Testis, Salivary Gland, Breast, Tonsil, Colon, Papillary, Follcular Carcinoma of Thyroid
Usage prévu
For In Vitro Diagnostic Use

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