BIO SB FOXP3 (EP340), RMab
For In Vitro Diagnostic Use
Description
FOXP3, also known as scurfin, is a protein involved in immune system responses. A member of the forkhead box protein family, FOXP3 appears to function as a transcription factor in the development and function of regulatory T cells. In regulatory T cell model systems, the FOXP3 transcription factor occupies the promoters of many important for regulatory T-cell function, and may repress transcription of key genes following stimulation of T cell receptors. Alterations in numbers of regulatory T-cells – in particular those that express FOXP3 antibody – are found in a number of disease states. Patients with tumors have a local relative excess of FOXP3 positive T cells which inhibits the body’s ability to suppress the formation of cancerous cells.
Synonymes
FOXP3, anti-FOXP3, anti FOXP3, forkhead box P3 (FOXP3), anti-forkhead box P3 (FOXP3), anti forkhead box P3 (FOXP3), forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), X-linked syndrome (IPEX) related, anti-forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti forkhead/winged-helix transcription regulator family member FOXP3 (forkhead box P3), anti-X-linked syndrome (IPEX) related, anti X-linked syndrome (IPEX) related, AIID, DIETER, forkhead box P3, Forkhead box protein P3, immune dysregulation polyendocrinopathy enteropathy X linked, immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, JM2, MGC141961, MGC141963, PIDX, Scurfin, XPID, FOXP3delta7, foxp
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP340
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Tonsil, Lymph Node, Thymus
- Usage prévu
- For In Vitro Diagnostic Use
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