BIO SB Factor XIIIa (EP292), RMab
For In Vitro Diagnostic Use
Description
Factor XIII or fibrin stabilizing factor is an enzyme of the blood coagulation system that crosslinks fibrin. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into Factor XIIIa; its activation into Factor XIIIa requires calcium as a cofactor. Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes, macrophages and dermal dendritic cells. Factor XIIIa antibody has been found to be useful in differentiating between Dermatofibroma (90% (+)), Dermatofibrosarcoma Protuberans (25%(+)) and Desmoplastic Malignant Melanoma (0%(+)). Factor XIIIa positivity is also seen in Capillary Hemagioblastoma (100%(+)), Hemangioendothelioma (100%(+)), Hemangiopericytoma (100%(+)), Xanthogranuloma (100%(+)), Xanthoma (100(+)), Hepatocellular Carcinoma (93%(+)), Glomus Tumor (80%(+)), and Meningioma 80%(+)).
Synonymes
bA525O21 1 coagulation factor XIII A1 polypeptide, Coagulation factor XIII A chain, coagulation factor XIII A polypeptide, coagulation factor XIII A1 polypeptide, coagulation factor XIIIa, F13A, factor XIIIa, anti-factor xiiia, anti factor xiiia, anti-factor 13a, anti factor 13a, fibrin stabilizing factor A subunit, fibrinoligase, FSF A subunit, protein glutamine gamma glutamyltransferase A chain, TGase, Transglutaminase A chain, transglutaminase plasma
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP292
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Placenta, Testis, Tonsil, Skin, Colon
- Usage prévu
- For In Vitro Diagnostic Use
Intéressé par ce produit ?
Indiquez la référence et le conditionnement souhaités, nous revenons vers vous rapidement.