BIO SB Cytokeratin HMW 34BE12 (34BE12), MMab
For In Vitro Diagnostic Use
Description
Cytokeratin HMW 34BE12 antibody is a High Molecular Weight cytokeratin that reacts with all squamous and ductal epithelium and stains carcinomas. This antibody recognizes cytokeratins 1, 5, 10, and 14 that are found in complex epithe-lia. Cytokeratin 34BE12 shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules or endometrial glands; there has been no reactivity with cells derived from simple epithelia. Nerve cells, glial cells and mesenchymal tissue such as blood vessels containing only non-keratin types of intermediate filaments are not labelled; however, reactivity with smooth-muscle cells has been occasionally observed. Mesenchymal Tumors, Lymphomas, Melanomas, Neural Tumors and Neuroendocrine Tumors are unreactive with this antibody. Cytokeratin 34BE12 has been shown to be useful in distinguishing Prostatic Adenocarcinoma from Hyperplasia of the Prostate.
Synonymes
anti-cytokeratin hmw 34be12, anti cytokeratin hmw 34be12, ck hmw 34be12, anti-ck hmw 34be12, anti ck hmw 34be12,
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- 34BE12
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Prostate, Cervix
- Usage prévu
- For In Vitro Diagnostic Use
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