BIO SB Cytokeratin 8 & 18 (B22.1/B23.1), MMab
For In Vitro Diagnostic Use
Description
Cytokeratin 8 belongs to the Type II (basic) subfamily of low molecular-weight keratins and exists in combination with Cytokeratin 18 (Type I [acidic] subfamily of low molecular weight keratins). They are perhaps the most commonly found products of the intermediate filament gene family, and are expressed in single-layer epithelial tissues of the body. Cytokeratins 8 antibody & cytokeratin 18 antibody can be found in most simple epithelium (e.g., thyroid, female breast, gastrointestinal tract, and respiratory tract). Adenocarcinomas and most Non-keratinizing Squamous Carcinomas will stain, but Keratinizing Squamous Carcinomas will not. This antibody is used when attempting to demonstrate the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells will stain. This approach facilitates the interpretation using immunostains and is more sensitive than mucin histochemistry.
Synonymes
KRT8, anti-ck8, anti ck8, anti-ck 8, CARD2, CK 8, CK8, CYK8, cytokeratin 8, K2C8, K8, keratin 8, keratin type II cytoskeletal 8, KO, type II keratin Kb8, keratin 18, KRT18, anti-Cytokeratin 18, anti Cytokeratin 18, anti-KRT18, anti KRT18, anti-Keratin 18, anti Keratin 18, cell proliferation inducing gene 46 protein, cell proliferation inducing protein 46, CK 18, CYK18, cytokeratin 18, K18, keratin type I cytoskeletal 18, CK18, Cytokeratin endo B, Endo B, keratin complex 1 acidic gene 18, Keratin D, Krt1 18, KRT5, Krt2 5, anti-ck18, anti ck18, anti-ck 18, ck8&18, anti-ck8&18, ck8 & 18, ck8 & ck18
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- B22.1 & B23.1
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Breast, Ovary, GI, Prostate, Pancreas, Salivary Gland
- Usage prévu
- For In Vitro Diagnostic Use
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