BIO SB Cytokeratin 5 & 6 (RM341), RMab
For In Vitro Diagnostic Use
Description
“Cytokeratin 5 (58 kDa) is a high-molecular weight, basic type of cytokeratin expressed in basal, intermediate and superficial-cell layers of stratified epithelia as well as transitional epithelia, complex epithelia, mesothelial cells and Mesothelioma. Cytokeratin 6 (56 kD) is also a high-molecular weight, basic type cytokeratin expressed by proliferating squamous epithelium often paired with Cytokeratin 16. Cytokeratin 5 & 6 antibody is positively seen in nearly 100% of Malignant Mesotheliomas and are rarely seen in Lung Adenocarcinomas. CK 5 and 6 can positively be seen in undifferentiated Large-cell Carcinoma as well as Squamous Carcinoma. Fewer than 10% of Carcinomas of the breast, colon, and prostate stain positively for this marker. Cytokeratin 5 & 6 antibody has also been used successfully as a myoepithelial cell marker in the prostate to determine malignancy.”
Synonymes
KRT6A, KRT6C, KRT5, KRT6B, anti-Cytokeratin 5/6, anti Cytokeratin 5/6, anti-KRT5, anti KRT5, KRT5, KRT6, KRT18, anti-KRT5, KRT6, anti KRT5, KRT6, Kertain 5, KRT6, Keratin 6, anti-Kertain 5, anti Kertain 5, anti-KRT6, anti KRT6, anti-Keratin 6, anti Keratin 6, aCK6A, CK6C, CK6D, cytokeratin 6A, cytokeratin 6C, cytokeratin 6D, K6A, K6C, K6D, keratin 6A, keratin epidermal type II K6A, Keratin type II cytoskeletal 6A, KRT6D, CK 6A, CK 6D, Type II keratin Kb6, anti-ck5, anti-ck6, anti ck5, anti ck6, anti-ck5&6, anti ck5&6
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RM341
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Prostate, Mesothelioma
- Usage prévu
- For In Vitro Diagnostic Use
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