Cytokeratin 4 (EP4), RMab
For In Vitro Diagnostic Use
Description
Cytokeratin 4 is a type II cytokeratin and is specifically found in differentiated layers of the mucosal and esophageal epithelia together with Cytokeratin 13. Mutations in the genes encoding this protein (KRT4) have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. A decreased expression of Cytokeratin 4 antibody is associated with head and neck squamous carcinoma. It is helpful in the differentiation of squamous cell carcinoma of esophagus origin from that of thyroid origin.
Synonymes
keratin 4, KRT4, anti-Cytokeratin 4, anti Cytokeratin 4, anti-Keratin 4, anti Keratin 4, anti-KRT4, anti KRT4, CK 4, CK4, anti-ck4, anti ck4, anti-ck 4, CYK4, cytokeratin 4, FLJ31692, K4, keratin type II cytoskeletal 4, type II keratin Kb4
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP4
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Cornea, Anus, Larynx, Pharynx, Tongue, Prostate, tonsil, Cervix, Squamous Epithelium, of Esophagus, Cervical Squamous Carcinomas
- Usage prévu
- For In Vitro Diagnostic Use
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