BIO SB Cytokeratin 20 (Ks20.8), MMab
For In Vitro Diagnostic Use
Description
Cytokeratin 20 (CK20) is a 46 kDa intermediate filament protein whose expression is restricted primarily to gastric and intestinal epithelium, urothelium, and Merkel cells. Cytokeratin 20 is a Type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells found in the gastric and intestinal mucosa. Cytokeratin 20 antibody is expressed in Adenocarcinomas of the colon, stomach, pancreas and biliary system. It is also expressed in Mucinous Ovarian Tumors, Transitional-cell Carcinomas of the urinary tract, and Merkel-cell Carcinomas. Cytokeratin 20 is useful in the differentiation of specific types of simple epithelial cells of the urinary tract and normal and malignantly-transformed epithelia. This antibody is essentially non-reactive in Squamous Cell Carcinomas and Adenocarcinomas of the Breast, Lung, and Endometrium, Non-mucinous Tumors of the Ovary, and Small-cell Carcinomas. This antibody is often used in conjunction with CK7 and other antibodies to distinguish Colon Carcinomas (CK20+) from Ovarian, Pulmonary, and Breast Carcinomas.
Synonymes
keratin 20, KRT20, anti-Cytokeratin 20, anti Cytokeratin 20, anti-KRT20, anti KRT20, anti-Keratin 20, anti Keratin 20, CD20, CK 20, CK20, anti-ck20, anti ck20, anti-ck 20, cytokeratin 20, K20, Keratin type I cytoskeletal 20, KRT21, MGC35423, Protein IT
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- Ks20.8
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Colon Carcinoma, Colon Mucosa, Bladder
- Usage prévu
- For In Vitro Diagnostic Use
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