BIO SB Cytokeratin 19 (RM364), RMab
For In Vitro Diagnostic Use
Description
Cytokeratin 19 is a Type I cytokeratin. Unlike its related family members, this smallest-known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically found in the periderm, the transiently-superficial layer that envelopes the developing epidermis. Cytokeratin 19 antibody reacts with a wide variety of epithelium and epithelial malignancies including Adenocar-cinomas of the colon, stomach, pancreas, biliary tract, liver and breast. Perhaps the most useful application is the identification of Thyroid Carcinoma of the papillary type, although Follicular Carcinoma is also labeled by this antibody approximately 50-60% of the time. Cytokeratin 19 is not expressed in hepatocytes; therefore, this antibody is useful in the identification of liver metastasis. The degree of Cytokeratin 19 positivity in Breast Cancer distinguishes malignant from benign tumors. Cytokeratin 19 is often coexpressed with Cytokeratin 7.
Synonymes
keratin 19, KRT19, anti-Cytokeratin 19, anti Cytokeratin 19, anti-KRT19, anti KRT19, anti-Keratin 19, anti Keratin 19, 40 kDa keratin intermediate filament, CK 19, CK19, anti-ck19, anti ck19, anti-ck 19, cytokeratin 19, K19, K1CS, keratin type I cytoskeletal 19, keratin type I 40 kd, MGC15366
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RM364
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Colon, Bladder, Thyroid Carcinoma, Colon Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use
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