BIO SB Claudin-5 (EP224), RMab
For In Vitro Diagnostic Use
Description
Claudin-5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction (TJ) strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-5 is an endothelial cell-specific component of TJ strands. Mutations in Claudin-5 have been found in patients with velocardiofacial syndrome. Claudin-5 antibody labels endothelial cells and has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudin-5 expression has been found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma, increased Claudin-5 expression is associated with aggressive behavior.
Synonymes
Claudin 5, CLDN5, claudin5, anti-claudin-5, anti claudin-5, anti-CLDN5, anti CLDN5, anti-claudin 5, anti-claudin5, anti claudin 5, anti claudin5, AWAL, BEC1, CPETRL1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP224
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Liver, Vascular Tissue, Placenta, Colon, Kidney, Fallopian Tube
- Usage prévu
- For In Vitro Diagnostic Use
Intéressé par ce produit ?
Indiquez la référence et le conditionnement souhaités, nous revenons vers vous rapidement.