BIO SB CD99 (BSB-9), MMab
For In Vitro Diagnostic Use
Description
CD99, also known as MIC-2 or single-chain Type-1 glycoprotein, is a human protein encoded by the CD99 gene. The protein has a MW of 32 kD. It is expressed on all leukocytes but highest on thymocytes, and is believed to augment T-cell adhesion and apoptosis of double-positive T-cells. It also participates in migration and activation. CD99 antibody expression is found on the cell membrane of Ewing’s Sarcoma and Primitive Peripheral Neuroectodermal Tumors (PNET). It is also present on a variety of other cell types including bone marrow, lymph nodes, spleen, cortical thymocytes, granulosa cells of the ovary, beta cells, CNS ependymal cells, Sertoli’s cells of the testis and a few endothelial cells. Mature granulocytes, however, tend to express very little or no CD99. CD99 antibody has also been identified in Lymphoblastic Lymphoma, Rhabdomyosarcoma, Mesenchymal Chondrosarcoma, and Thymoma.
Synonymes
CD99, anti-cd99, anti cd99, 12E7, antigen identified by monoclonal 12E7 Y homolog, antigen identified by monoclonal antibodies 12E7 F21 and O13, CD99 antigen, CD99 molecule, E2 antigen, MIC2, MIC2 monoclonal antibody 12E7, MIC2X, MIC2Y, Protein MIC2, surface antigen MIC2, T cell surface glycoprotein E2, HBA71, MSK5X
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-9
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Pancreas, Thymus, Ependyma, Ewing’s Sarcoma
- Usage prévu
- For In Vitro Diagnostic Use
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