BIO SB CD8 (EP334), RMab
For In Vitro Diagnostic Use
Description
CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule that is specific for the Class I MHC protein. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. CD8 antibody is a T-cell marker for the detection of cytotoxic/suppressor cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody is used to distinguish between reactive and neoplastic T-cells.
Synonymes
CD8B, CD8B1, CD8A, MAL, anti-CD8, anti CD8, anti-CD8A, anti CD8A, T-lymphocyte differentiation antigen T8/Leu-2, anti-MAL, anti MAL, anti-, anti , anti-T-lymphocyte differentiation antigen T8/Leu-2, anti T-lymphocyte differentiation antigen T8/Leu-2, CD8 antigen beta polypeptide 1 p37, CD8b molecule, Leu2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T cell surface glycoprotein CD8 beta chain, CD8, CD8 antigen alpha polypeptide p32, CD8a molecule, Leu2 T lymphocyte antigen, OKT8 T cell antigen, p32, T cell co receptor, T cell antigen Leu2, T cell surface glycoprotein CD8 alpha chain, T lymphocyte differentiation antigen T8 Leu 2, T8 T cell antigen, P37
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP334
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node, Liver, Colon
- Usage prévu
- For In Vitro Diagnostic Use
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