CD79a (JCB117), MMab
For In Vitro Diagnostic Use
Description
CD79a is non-covalently associated with membrane-bound immunoglobulins on B-cells to constitute the B-cell Ag receptor. CD79a first appears at pre B-cell stage and persists until the plasma-cell stage, where it is found as an intracellular component. CD79a is found in the majority of Acute Leukemias of precursor B-cell type, in B-cell lines, B-cell Lymphomas, and in some Myelomas. CD79a antibody is a B-cell marker that is generally used to complement CD20. This antibody will stain many of the same Lymphomas as CD20, but also stains more B-precursor Lymphoid Leukemias than CD20. CD79a antibody also stains more cases of Plasma-cell Myeloma and occasionally some types of endothelial cells as well. CD79a will stain many cases of Acute Promyelocytic Leukemia (FAB-M3), but only rarely stains other types of Myeloid Leukemia.
Synonymes
CD79A, anti-cd79a, anti cd79a, B cell antigen receptor complex associated protein alpha chain, CD79a antigen immunoglobulin associated alpha, CD79a molecule immunoglobulin associated alpha, Ig alpha, IGA, MB 1, MB 1 membrane glycoprotein, Membrane bound immunoglobulin associated protein, Surface IgM associated protein
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- JCB117
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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