BIO SB anticorps automates-ihc reactifs-auxiliaires

CD6 (BSB-54), MMab

For In Vitro Diagnostic Use

Clone BSB-54 IgG1 Mouse Monoclonal

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Description

CD6 (also known as Cluster of Differentiation 6) is a human protein encoded by the CD6 gene on Chromosome 11. CD6 antibody expression is found on the outer membrane of T-lymphocytes. The encoded CD6 protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. Studies have shown CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis.

Synonymes

CD6, CD6 antigen, CD6 molecule, FLJ44171, T cell differentiation antigen CD6, T12, TP120, anti-cd6, anti cd6

Caractéristiques

Type: Mouse Monoclonal
Clone: BSB-54
Isotype: IgG1
Réactivité: Paraffin, Frozen
Localisation: Membranous
Contrôle: Tonsil, Lymph Node, Prostate, Colon, Spleen
Usage prévu: For In Vitro Diagnostic Use

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