BIO SB CD57 (BSB-10), MMab
For In Vitro Diagnostic Use
Description
CD57 (NK-1) recognizes an oligosaccharide (MW 100-110 kDa) antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system. Follicular Center-cell Lymphomas often contain many NK cells within the neoplastic follicles. CD57 antibody (NK-1) reportedly also reacts with a variety of cell types in non-lymphoid tissues. CD57 antibody stains neuroendocrine cells and their tumors, including Carcinoid Tumor and Medulloblastomas. CD57 also reacts with a variety of cell types in non-lymphoid tissues, including Neurofibroma, Ganglioneuroma, and Prostate Carcinoma.
Synonymes
B3GAT1, anti-cd57, anti cd57, Beta 1 3 glucuronyltransferase 1, beta 1 3 glucuronyltransferase 1 glucuronosyltransferase P, CD57, CD57 antigen, Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1, GlcAT P, GLCATP, GlcUAT P, Glucuronosyltransferase P, HNK 1, HNK1, LEU7, LEU7 antigen, NK 1, UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase, GLCUATP, NK1, anti-nk1, anti nk1
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-10
- Isotype
- IgM/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
Intéressé par ce produit ?
Indiquez la référence et le conditionnement souhaités, nous revenons vers vous rapidement.